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Welcome

Since September 2019, I have been Assistant Professor (Maître de Conférences) in statistics at Université de Paris.
From January 2016 to August 2019, I have been a postdoctoral fellow in Ron Do’s lab at the Icahn School of Medicine at Mount Sinai, in New York, USA.
Before joining the Institute for Personalized Medicine at Mount Sinai, I was a BioStatistician at the laboratory of Genomics and metabolic diseases of the Institut Pasteur in Lille, France.

I defended my PhD thesis, “Exploratory Analysis of transcriptomic data: from their visualisation to the integration of external information” on the 4th of September, 2013 in Agrocampus Ouest, Rennes, France.

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News

Editorial in Science citing our Science advances paper Duffy et al. (2020)

Editorial mentioning papers using data from the Genotype-Tissue Expression (GTEx) Project.

  • [2020,misc] bibtex Go to document
    The Genotype-Tissue Expression Project, 2020.
    @misc{noauthor_genotype-tissue_2020, title = {The {Genotype}-{Tissue} {Expression} {Project}},
      url = {https://www.sciencemag.org/collections/genetic-variation},
      language = {en},
      urldate = {2020-09-11},
      journal = {Science {\textbar} AAAS},
      month = sep, year = {2020},
      file = {Snapshot:/Users/travail/Zotero/storage/33IZEH9D/genetic-variation.html:text/html}
    }

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Science advances

Check out our paper “Tissue-specific genetic features inform prediction of drug side effects in clinical trials” in Science Advances

  • [2020,article] bibtex Go to document
    A. Duffy*, M. Verbanck*, A. Dobbyn*, H. Won, J. L. Rein, I. S. Forrest, G. Nadkarni, G. Rocheleau, and R. Do, Tissue-specific genetic features inform prediction of drug side effects in clinical trials, Science Advances, vol. 6, iss. 37, p. 6242, 2020.
    @article{duffy_tissue-specific_2020, title = {Tissue-specific genetic features inform prediction of drug side effects in clinical trials},
      volume = {6},
      copyright = {Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.},
      issn = {2375-2548},
      url = {https://advances.sciencemag.org/content/6/37/eabb6242},
      doi = {10.1126/sciadv.abb6242},
      language = {en},
      number = {37},
      urldate = {2020-09-11},
      journal = {Science Advances},
      author = {Duffy*, Aine and Verbanck*, Marie and Dobbyn*, Amanda and Won, Hong-Hee and Rein, Joshua L. and Forrest, Iain S. and Nadkarni, Girish and Rocheleau, Ghislain and Do, Ron},
      month = sep, year = {2020},
      note = {Publisher: American Association for the Advancement of Science Section: Research Article},
      pages = {eabb6242}
    }

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Genome Biology

Check out our paper “HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases” in Genome Biology

  • [2019,article] bibtex Go to document
    D. M. Jordan*, M. Verbanck*, and R. Do, HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases, Genome Biology, vol. 20, iss. 1, p. 222, 2019.
    @article{jordan_hops:_2019, title = {{HOPS}: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases},
      volume = {20},
      issn = {1474-760X},
      url = {https://doi.org/10.1186/s13059-019-1844-7},
      number = {1},
      urldate = {2019-11-06},
      journal = {Genome Biology},
      author = {Jordan*, Daniel M. and Verbanck*, Marie and Do, Ron},
      month = oct, year = {2019},
      pages = {222}
    }

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Verbanck et al. Nature Genetics (2018): press releases about our MR-PRESSO paper

  • Leading genetics study method may need reconsideration, significant distortions discovered MedicalXpress
  • Leading genetics study method may need reconsideration, significant distortions discovered: Study of Mendelian randomization results detects factor called horizontal pleiotropy in close to 50 percent of significant causal relationships, a finding of great importance for detecting biomarkers for drug development and disease management Science Daily
  • Researchers discover significant distortions in leading genetics study method The Medical News
  • Leading Genetics Study Method May Need Reconsideration, Significant Distortions Discovered Science Newsline
  • Source of Potential Bias Widespread in Large Genetic Studies The Scientist Magazine

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PLOS MEDICINE

The article “No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study” has been published

  • [2019,article] bibtex Go to document
    D. M. Jordan*, H. K. Choi*, M. Verbanck*, R. Topless, H. Won, G. Nadkarni, T. R. Merriman, and R. Do, No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study, PLOS Medicine, vol. 16, iss. 1, p. 1002725, 2019.
    @article{jordan_no_2019, title = {No causal effects of serum urate levels on the risk of chronic kidney disease: {A} {Mendelian} randomization study},
      volume = {16},
      issn = {1549-1676},
      shorttitle = {No causal effects of serum urate levels on the risk of chronic kidney disease},
      url = {https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002725},
      doi = {10.1371/journal.pmed.1002725},
      language = {en},
      number = {1},
      urldate = {2019-01-16},
      journal = {PLOS Medicine},
      author = {Jordan*, Daniel M. and Choi*, Hyon K. and Verbanck*, Marie and Topless, Ruth and Won, Hong-Hee and Nadkarni, Girish and Merriman, Tony R. and Do, Ron},
      month = jan, year = {2019},
      keywords = {Epidemiology, Genetics of disease, Gout, Chronic kidney disease, Genetic epidemiology, Genome-wide association studies, Instrumental variable analysis, Metaanalysis},
      pages = {e1002725},
      }

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Nature Genetics

The article “Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases” has been published

  • [2018,article] bibtex Go to document
    M. Verbanck*, C. Chen*, B. Neale, and R. Do, Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases, Nature Genetics, p. 1, 2018.
    @article{verbanck_detection_2018, title = {Detection of widespread horizontal pleiotropy in causal relationships inferred from {Mendelian} randomization between complex traits and diseases},
      copyright = {2018 The Author(s)},
      issn = {1546-1718},
      url = {https://www.nature.com/articles/s41588-018-0099-7},
      doi = {10.1038/s41588-018-0099-7},
      language = {en},
      urldate = {2018-04-23},
      journal = {Nature Genetics},
      author = {Verbanck*, Marie and Chen*, Chia-Yen and Neale, Benjamin and Do, Ron},
      month = apr, year = {2018},
      pages = {1},
      }

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PLOS ONE

The article “Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles” has been published

  • [2017,article] bibtex Go to document
    M. Verbanck*, M. Canouil*, A. Leloire, V. Dhennin, X. Coumoul, L. Yengo, P. Froguel, and O. Poulain-Godefroy, Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles, PLOS ONE, vol. 12, iss. 6, p. 0179583, 2017.
    @article{verbanck_low-dose_2017, title = {Low-dose exposure to bisphenols {A},
      {F} and {S} of human primary adipocyte impacts coding and non-coding {RNA} profiles},
      volume = {12},
      issn = {1932-6203},
      url = {http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179583},
      doi = {10.1371/journal.pone.0179583},
      number = {6},
      urldate = {2017-06-19},
      journal = {PLOS ONE},
      author = {Verbanck*, Marie and Canouil*, Mickaël and Leloire, Audrey and Dhennin, Véronique and Coumoul, Xavier and Yengo, Loïc and Froguel, Philippe and Poulain-Godefroy, Odile},
      month = jun, year = {2017},
      keywords = {Gene regulation, Adipocytes, MicroRNAs, Adipocyte differentiation, Pollutants, Small nucleolar RNAs, Microarrays, Non-coding RNA},
      pages = {e0179583},
      }

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PLOS ONE

The article “Post-Bariatric Surgery Changes in Quinolinic and Xanthurenic Acid Concentrations Are Associated with Glucose Homeostasis” has just been published

  • [2016,article] bibtex Go to document
    M. Favennec*, B. Hennart*, M. Verbanck*, M. Pigeyre, R. Caiazzo, V. Raverdy, H. Verkindt, A. Leloire, G. J. Guillemin, L. Yengo, D. Allorge, P. Froguel, F. Pattou, and O. Poulain-Godefroy, Post-Bariatric Surgery Changes in Quinolinic and Xanthurenic Acid Concentrations Are Associated with Glucose Homeostasis, PLOS ONE, vol. 11, iss. 6, p. 0158051, 2016.
    @article{favennec_post-bariatric_2016, title = {Post-{Bariatric} {Surgery} {Changes} in {Quinolinic} and {Xanthurenic} {Acid} {Concentrations} {Are} {Associated} with {Glucose} {Homeostasis}},
      volume = {11},
      issn = {1932-6203},
      url = {http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158051},
      doi = {10.1371/journal.pone.0158051},
      number = {6},
      urldate = {2016-06-22},
      journal = {PLOS ONE},
      author = {Favennec*, Marie and Hennart*, Benjamin and Verbanck*, Marie and Pigeyre, Marie and Caiazzo, Robert and Raverdy, Violeta and Verkindt, Hélène and Leloire, Audrey and Guillemin, Gilles J. and Yengo, Loïc and Allorge, Delphine and Froguel, Philippe and Pattou, François and Poulain-Godefroy, Odile},
      month = jun, year = {2016},
      keywords = {Obesity, Digestive system procedures, Surgical and invasive medical procedures, Tryptophan, Diabetes mellitus, Glucose metabolism, Weight loss, Serotonin},
      pages = {e0158051},
      }

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First day at Mount Sinai

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Vidéo soutenance de thèse

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Statistics and Computing

The article “Regularised PCA to denoise and visualise data” has just been published

  • [2013,article] bibtex Go to document
    M. Verbanck, J. Josse, and F. Husson, Regularised PCA to denoise and visualise data, Statistics and Computing, vol. 25, iss. 2, pp. 471-486, 2013.
    @article{verbanck2013SetC, title = {Regularised {PCA} to denoise and visualise data},
      volume = {25},
      issn = {0960-3174, 1573-1375},
      url = {http://link.springer.com/article/10.1007/s11222-013-9444-y},
      doi = {10.1007/s11222-013-9444-y},
      language = {en},
      number = {2},
      urldate = {2016-07-25},
      journal = {Statistics and Computing},
      author = {Verbanck, Marie and Josse, Julie and Husson, François},
      month = dec, year = {2013},
      pages = {471--486},
      }

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PhD defense, 4th september, Agrocampus Ouest

“Exploratory Analysis of transcriptomic data: from their visualisation to the integration of external information”

Examination committee:

  • Hervé Abdi (University of Texas at Dallas, USA), Rapporteur
  • Philippe Besse (Institut de Mathématiques de Toulouse, France),Rapporteur
  • Sandrine Lagarrigue (INRA/Agrocampus Ouest, Rennes, France), Examinatrice
  • Jean Mosser (CNRS Université de Rennes 1, France), Examinateur
  • Jérôme Pagès (Agrocampus Ouest, Rennes, France), Directeur de thèse
  • Sébastien Lê (Agrocampus Ouest, Rennes, France), Directeur de thèse

 

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Festival Sciences en Cour[t]s 2013

On the 18th of april 2013, will take place the festival Sciences en Cour[t]s in Rennes. Sciences en Cour[t]s is a festival where Ph.D candidates realize very short movies of popular science about their research.

More information at
www.sciences-en-courts.fr

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BMC Bioinformatics

The article “A new unsupervised gene clustering algorithm based on the integration of biological knowledge into expression data” has just been published

  • [2013,article] bibtex Go to document
    M. Verbanck, S. Lê, and J. Pagès, A new unsupervised gene clustering algorithm based on the integration of biological knowledge into expression data, BMC Bioinformatics, vol. 14, p. 42, 2013.
    @article{verbanck2013bmc, title = {A new unsupervised gene clustering algorithm based on the integration of biological knowledge into expression data},
      volume = {14},
      issn = {1471-2105},
      url = {http://dx.doi.org/10.1186/1471-2105-14-42},
      doi = {10.1186/1471-2105-14-42},
      urldate = {2016-06-22},
      journal = {BMC Bioinformatics},
      author = {Verbanck, Marie and Lê, Sébastien and Pagès, Jérôme},
      year = {2013},
      pages = {42},
      }

Open AccessHighly Accessed

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Un article dans la revue “Sciences Ouest”

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StatistiX et le problème de la potion magique

On the occasion of Sciences en Cour[t]s 2012, Cécile Sauder and I won three prices for our very short movie about statistics: the student prize favorite, the public prize favorite and finally the 1st price of the judges panel.

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Festival Sciences en Cour[t]s 2012

On the 5th of april 2012, will take place the festival Sciences en Cour[t]s in Rennes. Sciences en Cour[t]s is a festival where Ph.D candidates realize very short movies of popular science about their research.

I am presenting a very short movie with Cécile Sauder about statistics which is called “StatistiX et le problème de la potion magique”

 

More information at
www.sciences-en-courts.fr

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PhD Graduation Ceremony

I recently took part in the first ever Ph.D Graduation of Agrocampus and cohosted the ceremony with a fellow Ph.D candidate Yuna Blum. Congratulations to the 28 Doctors of 2010-2011.

 

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