Since September 2019, I have been Assistant Professor (Maître de Conférences) in statistics at Université de Paris.
From January 2016 to August 2019, I have been a postdoctoral fellow in Ron Do’s lab at the Icahn School of Medicine at Mount Sinai, in New York, USA.
Before joining the Institute for Personalized Medicine at Mount Sinai, I was a BioStatistician at the laboratory of Genomics and metabolic diseases of the Institut Pasteur in Lille, France.
I defended my PhD thesis, “Exploratory Analysis of transcriptomic data: from their visualisation to the integration of external information” on the 4th of September, 2013 in Agrocampus Ouest, Rennes, France.
PleioMap: project funded by the Agence Nationale de la Recherche
The PleioMap project aiming at leveraging pleiotropy in human genetic architecture to build a map of pleiotropy using machine learning has been funded by the French National Research agency (ANR JCJC, PI: Marie Verbanck).
As part of the project, a 2-year postdoctoral position is available. More information here.
Editorial in Science citing our Science advances paper Duffy et al. (2020)
Editorial mentioning papers using data from the Genotype-Tissue Expression (GTEx) Project.
Check out our paper “Tissue-specific genetic features inform prediction of drug side effects in clinical trials” in Science Advances
Check out our paper “HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases” in Genome Biology
Verbanck et al. Nature Genetics (2018): press releases about our MR-PRESSO paper
- Leading genetics study method may need reconsideration, significant distortions discovered MedicalXpress
- Leading genetics study method may need reconsideration, significant distortions discovered: Study of Mendelian randomization results detects factor called horizontal pleiotropy in close to 50 percent of significant causal relationships, a finding of great importance for detecting biomarkers for drug development and disease management Science Daily
- Researchers discover significant distortions in leading genetics study method The Medical News
- Leading Genetics Study Method May Need Reconsideration, Significant Distortions Discovered Science Newsline
- Source of Potential Bias Widespread in Large Genetic Studies The Scientist Magazine
The article “No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study” has been published
The article “Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases” has been published
The article “Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles” has been published
The article “Post-Bariatric Surgery Changes in Quinolinic and Xanthurenic Acid Concentrations Are Associated with Glucose Homeostasis” has just been published
First day at Mount Sinai
Vidéo soutenance de thèse
Statistics and Computing
The article “Regularised PCA to denoise and visualise data” has just been published
PhD defense, 4th september, Agrocampus Ouest
“Exploratory Analysis of transcriptomic data: from their visualisation to the integration of external information”
- Hervé Abdi (University of Texas at Dallas, USA), Rapporteur
- Philippe Besse (Institut de Mathématiques de Toulouse, France),Rapporteur
- Sandrine Lagarrigue (INRA/Agrocampus Ouest, Rennes, France), Examinatrice
- Jean Mosser (CNRS Université de Rennes 1, France), Examinateur
- Jérôme Pagès (Agrocampus Ouest, Rennes, France), Directeur de thèse
- Sébastien Lê (Agrocampus Ouest, Rennes, France), Directeur de thèse
On the 18th of april 2013, will take place the festival Sciences en Cour[t]s in Rennes. Sciences en Cour[t]s is a festival where Ph.D candidates realize very short movies of popular science about their research.
More information at
The article “A new unsupervised gene clustering algorithm based on the integration of biological knowledge into expression data” has just been published
Un article dans la revue “Sciences Ouest”
StatistiX et le problème de la potion magique
On the occasion of Sciences en Cour[t]s 2012, Cécile Sauder and I won three prices for our very short movie about statistics: the student prize favorite, the public prize favorite and finally the 1st price of the judges panel.
Festival Sciences en Cour[t]s 2012
On the 5th of april 2012, will take place the festival Sciences en Cour[t]s in Rennes. Sciences en Cour[t]s is a festival where Ph.D candidates realize very short movies of popular science about their research.
I am presenting a very short movie with Cécile Sauder about statistics which is called “StatistiX et le problème de la potion magique”
More information at
PhD Graduation Ceremony
I recently took part in the first ever Ph.D Graduation of Agrocampus and cohosted the ceremony with a fellow Ph.D candidate Yuna Blum. Congratulations to the 28 Doctors of 2010-2011.